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Headlines Tagged with Health/Science 68,914 headlines found

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Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations

We define how chronic cigarette smoke-induced time-dependent epigenetic alterations can sensitize human bronchial epithelial cells for transformation by a single oncogene. The smoke-induced chromatin changes include initial repressive polycomb marking of
Cell
added Sep 12, 2017 11:16
5 Views

'Epigenetic' changes from cigarette smoke may be first step in lung cancer development

"Our study suggests that epigenetic changes to cells treated with cigarette smoke sensitize airway cells to genetic mutations known to cause lung cancers," says Stephen Baylin, M.D., the Virginia and D.K. Ludwig Professor for Cancer Research and professo
Medical Xpress (PhysOrg.com)
added Sep 12, 2017 11:15
9 Views

Availability and Placement of Electronic Nicotine Delivery Systems at the Point-of-Sale

Pharmacies placed cigalikes with cessation aids behind the counter suggesting their ability to aid in smoking cessation. Most convenience stores placed ENDS in self-service locations, making them easily accessible to youth. Findings highlight the need for
Nicotine and Tobacco Research
added Sep 12, 2017 11:02
2 Views

Facilitated Extinction Training to Improve Pharmacotherapy for Smoking Cessation: A Pilot Feasibility Trial

Feasibility was demonstrated. Participants adhered to the FE intervention, thereby optimizing the number and variety of extinction trials. Findings support testing the novel FE smoking cessation intervention in a fully-powered trial.
Nicotine and Tobacco Research
added Sep 12, 2017 11:02
6 Views

Sex differences in subjective responses to moderate versus very low nicotine content cigarettes

Relative to men, women’s subjective responses to acute smoking are less sensitive to differences in cigarette nicotine content. To our knowledge, this is the first comparison of sex differences in response to very carefully controlled doses of smoked nic
Nicotine and Tobacco Research
added Sep 12, 2017 11:02
3 Views

Network analysis of intrinsic functional brain connectivity in male and female adult smokers: A Preliminary Study

Network communication was altered in smokers, primarily in limbic and salience network regions. Network topology was associated with nicotine dependence in male but not female smokers in regions associated with reinforcement (nucleus accumbens) and cravi
Nicotine and Tobacco Research
added Sep 12, 2017 11:02
3 Views

Using Elastic Net Penalized Cox Proportional Hazards Regression to Identify Predictors of Imminent Smoking Lapse

The strongest predictors of smoking lapse were environmental in nature (e.g., being in smoking-permitted areas) as opposed to internal factors such as psychological affect. Interventions may be improved by a renewed focus of interventions on these predic
Nicotine and Tobacco Research
added Sep 12, 2017 11:02
6 Views

A qualitative evaluation of mental health clinic staff perceptions of barriers and facilitators to treating tobacco use

VA mental health staff struggle with knowing that tobacco use is important, but they face competing priorities, encounter patient resistance, are conflicted on their role in addressing tobacco, and lack tobacco training. They suggested strategies at mult
Nicotine and Tobacco Research
added Sep 12, 2017 11:01
6 Views

Healthcare Utilization and Expenditures Attributable to Smokeless Tobacco Use among US Adults

Comprehensive tobacco control policies and interventions are needed to reduce ST use and the associated healthcare burden. This is the first study to assess the impact of smokeless tobacco (ST) use on healthcare burden in the US. Findings indicate that
Nicotine and Tobacco Research
added Sep 12, 2017 11:01
2 Views

[Korea - South, USA] Differences in adolescent e-cigarette and cigarette prevalence in two policy environments: South Korea and the United States

In Korea, where e-cigarettes are extensively regulated, adolescent e-cigarette use remained stable at a low level, whereas in the United States, where e-cigarette regulation has been limited, e-cigarette use increased. Combined e-cigarette plus cigarette
Nicotine and Tobacco Research
added Sep 12, 2017 11:01
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