Sort by: Date added | Date Published | Most Viewed

Headlines Tagged with Genes 1,669 headlines found


Smoking a Pack a Day for a Year Leaves 150 Mutations in Every Lung Cell

examined the DNA of more than 3,000 tumors from the bodies of smokers and nonsmokers. The results, published this week in the journal Science, were sobering: Researchers found deep molecular “signatures” etched in tumor cells, even in organs that were nev
Smithsonian Magazine
added Nov 4, 2016 16:48

[UK] DNA study lays bare devastating damage caused by smoking

The devastating impact of cigarette smoke on the body’s DNA has been laid bare by the first comprehensive study into the damage tobacco inflicts on human cells. People who smoke a pack of cigarettes each day for a year develop on average 150 extra mutat
The Guardian (uk)
added Nov 4, 2016 14:45

Smoking a pack a day causes 150 mutations in every lung cell, research shows

researchers said the findings show a direct link between the number of cigarettes smoked in a lifetime and the number of mutations in the DNA of cancerous tumors. The highest mutation rates were seen in lung cancers, but tumors in other parts of the body
added Nov 3, 2016 21:33

Smoking a Pack a Day for a Year Causes 150 Mutations in Lung Cells

"This study of smoking tells us that looking in the DNA of cancers can provide provocative new clues to how cancers develop and thus, potentially, how they can be prevented." Scientists have measured the catastrophic genetic damage caused by smoking in
The Science Explorer (ca)
added Nov 3, 2016 21:17

Mutational signatures associated with tobacco smoking in human cancer [FREE FULL TEXT]

Consistent with the proposition that an increased mutation load caused by tobacco smoke contributes to increased cancer risk, the total mutation burden is elevated in smokers versus nonsmokers with lung adenocarcinoma, larynx, liver, and kidney cancers. H
added Nov 3, 2016 21:17

[Pennsylvania] Smoking-Linked Cancer Mutations Mapped

A comprehensive survey of mutations likely caused by carcinogens found in tobacco smoke by researchers at the Los Alamos National Laboratory in New Mexico, the Wellcome Trust Sanger Institute, and their colleagues was published today (November 3) in Scie
The Scientist
added Nov 3, 2016 21:17
1 View

Mutational signatures mark cancer's smoking gun

A broad computational study of cancer genome sequences identifies telltale mutational signatures associated with smoking tobacco and demonstrates, for the first time, that smoking increases cancer risk by causing somatic mutations in tissues directly and
added Nov 3, 2016 21:17

Understanding the role of genes in smoking addiction, nicotine withdrawal

While there isn't one explanation for why it is so difficult to quit smoking or why some people are successful and others are not, understanding genetics may be one piece of the puzzle, Gould said. "I realized in addition to studying the effects of nicot
Medical Xpress (
added Oct 18, 2016 19:03

Exposure of Human Lung Cells to Tobacco Smoke Condensate Inhibits the Nucleotide Excision Repair Pathway [FREE FULL TEXT]

our findings indicate that inhibition of NER is another mechanism by which smoking may contribute to development of lung cancer. Therefore, it may be prudent to consider measuring individual DNA repair capacity as a means of evaluating lung cancer risk, p
PLoS (Public Library of Science)
added Oct 17, 2016 19:02

Study finds a new way that tobacco smoke can cause cancer

illuminates a new way that tobacco smoke may promote the development of lung cancer: inhibiting a DNA repair process called nucleotide excision repair (NER)... Many components of tobacco smoke are carcinogens that can damage DNA. This damage must be remov
Medical Xpress (
added Oct 17, 2016 19:01
Sign up for daily headlines All Headlines Featured Headlines U.S. Headlines International Headlines