http://www.tobacco.org/newsfeed/category/breast_cancer.rss Latest top tobacco news headlines en-us http://www.medwire-news.md/46/75807/Oncology/Tobacco_smoke_exposure_does_not_increase_breast_cancer_risk.html http://tobacco.org/news/267261.html Exposure to tobacco smoke during childhood or as an adult does not increase the risk for developing breast cancer among women who have never smoked, a large prospective study has shown. The researchers claim that previous positive findings from retrospective studies suggesting such a link have been distorted by the fact that women were more likely to report past exposures because they knew that they had breast cancer. . . . As reported in the International Journal of Epidemiology, women who were exposed to passive smoke as children were at no greater risk for developing breast cancer than those who were not exposed (adjusted relative risk [RR]=0.98), nor were women who were exposed as adults (RR=1.02). MedWire News Thu, 19 Jun 2008 04:00:00 GMT http://www.springerlink.com/content/x339uv595214872m/ http://tobacco.org/news/266225.html We evaluated the association between smoking and risk of breast cancer in non-Hispanic white (NHW) and Hispanic or American Indian (HAI) women living in the Southwestern United States. . . . Passive smoke increased risk of pre-menopausal breast cancer for HAI women (OR 1.9, 95% CI 1.1–3.1 everyone; OR 2.3, 95% CI 1.2–4.5 nonsmokers). HAI pre-menopausal women who were exposed to 10+ h of passive smoke per week and had the rs2069832 IL6 GG genotype had over a fourfold increased risk of breast cancer (OR 4.4, 95% CI 1.5–12.8; P for interaction 0.01). Those with the ESR1 Xba1 AA genotype had a threefold increased risk of breast cancer if they smoked ≥15 pack-years relative to non-smokers (P interaction 0.01). These data suggest that breast cancer risk is associated with active and passive smoking. Breast Cancer marty.slattery@hsc.utah.edu Sat, 31 May 2008 04:00:00 GMT http://www.medwire-news.md/46/74652/Oncology/Genotype-cigarette_smoke_interaction_shown_in_breast_cancer.html http://tobacco.org/news/264483.html Cigarette smoke exposure substantially increases the risk for developing breast cancer among premenopausal women with certain polymorphisms in interleukin 6 (IL6) and estrogen receptor alpha (ESR1), results of a case-control study demonstrate. The findings add to a growing body of evidence suggesting that genotype and cigarette smoke can interact to increase the risk for breast cancer. One study recently reported by MedWire News found that smokers with the slow-metabolizing N-acetyltransferase 2 genotype face an increased risk for the disease compared with non-smokers. For the present study, Martha Slattery (University of Utah, Salt Lake City, USA) and colleagues enrolled 3128 non-Hispanic White women, including 1527 with breast cancer and 1601 controls, along with 798 cases and 924 controls of Hispanic/American Indian ethnicity. . . . Notably, exposure to more than 10 hours of passive smoke per week was associated with a 3.0- and 4.4-fold increased breast cancer risk in Hispanic/American Indian and non-Hispanic White premenopausal GG rs2069832 carriers, respectively, compared with women with the wild-type genotype who reported less than 1 hour of exposure. In addition women of either ethnicity group who smoked more than 15 cigarette pack-years and had the ESR1 Xba1 AA genotype faced a 3-fold increased risk for breast cancer compared with nonsmokers with the wild-type allele. "Our data suggest that this risk may be influenced by underlying genetic susceptibility and that mechanisms involving both estrogen and inflammation may be important in defining risk," Slattery and colleagues conclude in the journal Breast Cancer Research and Treatment. MedWire News Tue, 29 Apr 2008 04:00:00 GMT http://thedartmouth.com/2008/03/07/news/smoke/ http://tobacco.org/news/261012.html Secondhand smoke increases the risk of breast cancer in young women, although many experts still refuse to accept the research, published by the California Environmental Protection Agency in 2006, because no study has conclusively linked direct smoke inhalation to breast cancer, Dr. Stan Glantz, director of the Center for Tobacco Control Research and Education at the University of California, San Francisco, claimed in his Thursday lecture at the Dartmouth-Hitchcock Medical Center. Glantz likened the breast cancer researchers who doggedly oppose the California EPA’s findings to “religious fanatics,” referring to their unwillingness to accept the findings. The link between smoke inhalation and breast cancer, which Glantz called “the most important scientific development in the last 10 years,” follows logically, according to Glantz, because cigarettes contain many known mammary carcinogens, such as benzene. The Dartmouth editor@thedartmouth.com ( Michael Coburn, The Dartmouth Staff) Fri, 07 Mar 2008 05:00:00 GMT http://tobaccofreekids.org/reports/products/downloads/2008NewProductsReport.pdf http://tobacco.org/news/260124.html Can Cancer Be Prevented? All cancers caused by cigarette smoking and heavy use of alcohol could be prevented completely. The American Cancer Society estimates that in 2008 about 170,000 cancer deaths are expected to be caused by tobacco use. Campaign for Tobacco-Free Kids Wed, 20 Feb 2008 05:00:00 GMT http://www.cancer.org/downloads/STT/CAFF2006HispPWSecured.pdf http://tobacco.org/news/260108.html Cancer Facts & Figures for Hispanics 2006-2008 Summarizes recent information on cancer occurrence and cancer screening in the Hispanic/Latino population, estimating the number of new cancer cases and deaths for 2006. Includes sections on use of cancer screening examinations, and cancer risk factors such as tobacco use and obesity. File Format: Adobe Acrobat File Size: 500k American Cancer Society Wed, 20 Feb 2008 05:00:00 GMT http://www.cancer.org/downloads/STT/CAFF2007AAacspdf2007.pdf http://tobacco.org/news/260106.html Estimates the number of new cancer cases and deaths for 2007 and provides the most recent statistics on cancer incidence, mortality, and five-year relative survival. Also includes sections on cancer risk factors such as tobacco use, physical activity, and use of cancer screening examinations. File Format: Adobe Acrobat File Size: 500k American Cancer Society Wed, 20 Feb 2008 05:00:00 GMT http://www.cancer.org/downloads/STT/2008CAFFfinalsecured.pdf http://tobacco.org/news/260105.html Lung and Bronchus New cases: An estimated 215,020 new cases are expected in 2008, accounting for about 15% of cancer diagnoses. The incidence rate is declining significantly in men, from a high of 102 cases per 100,000 in 1984 to 73.6 in 2004. In women, the rate is approaching a plateau after a long period of increase. Lung cancer is classified clinically as small cell (13%) or non-small cell (87%) for the purposes of treatment. Deaths: Lung cancer accounts for the most cancerrelated deaths in both men and women. An estimated 161,840 deaths, accounting for about 29% of all cancer deaths, are expected to occur in 2008. Since 1987, more women have died each year from lung cancer than from breast cancer. Death rates among men decreased by 1.3% per year from 1990-1994 and by 2.0% per year from 1994- 2004. Female lung cancer death rates are approaching a plateau after continuously increasing for several decades. These trends in lung cancer mortality reflect the decrease in smoking rates over the past 30 years. . . . Survival: The 1-year relative survival for lung cancer has slightly increased from 35% in 1975-1979 to 41% in 2000- 2003, largely due to improvements in surgical techniques and combined therapies. However, the 5-year survival rate for all stages combined is only 15%. The survival rate is 49% for cases detected when the disease is still localized, but only 16% of lung cancers are diagnosed at this early stage. American Cancer Society Wed, 20 Feb 2008 05:00:00 GMT http://www.washingtonpost.com/wp-dyn/content/article/2008/02/19/AR2008021902398.html http://tobacco.org/news/260102.html Women who live in neighborhoods with large amounts of nighttime illumination are more likely to get breast cancer than those who live in areas where nocturnal darkness prevails, according to an unusual study that overlaid satellite images of Earth onto cancer registries. The finding adds credence to the hypothesis that exposure to too much light at night can raise the risk of breast cancer by interfering with the brain's production of a tumor-suppressing hormone. . . . They obtained satellite data from NASA that showed in great detail how much light was emitted spaceward from neighborhoods throughout Israel. . . . The team then overlaid that map with local statistics on cases of breast cancer and, for comparison, lung cancer, which is caused mostly by smoking and so would not be expected to be linked to light. . . . the researchers found no link between night lighting and lung cancer, they report in this week's online issue of the journal Chronobiology International. The Washington Post Thu, 21 Feb 2008 05:00:00 GMT http://www.asco.org/ASCO/News/Cancer%20News?&reuterview=detail_view&reutersid=7930 http://tobacco.org/news/259793.html Researchers have confirmed yet another ill effect of smoking cigarettes: it increases the risk of breast cancer in women with a common genetic variation. The gene involved, N-acetyltransferase 2 (NAT2), is believed to help clear the body of aromatic amines, a major carcinogen in tobacco smoke. The researchers found that women with the slower-acting form of this gene -- who represent 50 percent to 60 percent of the white population and 35 percent to 40 percent of African-Americans -- are more likely to get breast cancer if they smoke. But the study's lead author said the finding shouldn't motivate people to undergo; instead, she said, it should spur them to quit smoking. "We still know very little about what these genes do and how they might affect risk-we think the most important thing for people to do is to live a healthy lifestyle," Dr. Christine B. Ambrosone of the Roswell Park Cancer Institute in Buffalo, New York, told Reuters Health. Reuters Thu, 14 Feb 2008 05:00:00 GMT http://www.sciencedaily.com/releases/2008/02/080206210814.htm http://tobacco.org/news/259549.html Women who smoke and have a specific genetic makeup are at significant risk for the development of breast cancer, according to a recent study published by the journal Cancer Epidemiology, Biomarkers and Prevention. A research group led by Christine Ambrosone, PhD, Cancer Prevention and Population Sciences Program, Roswell Park Cancer Institute (RPCI) and Jenny Chang-Claude, PhD, Professor in Epidemiology at University of Heidelberg analyzed data from 10 of the 13 studies published in the last 10 years in which they evaluated genetic information, smoking habits and breast cancer risk in 4,889 premenopausal and 7,033 postmenopausal women. Analysis demonstrated a significant interaction between breast cancer risk, smoking, and a specific gene called the NAT2 that produces the enzyme, N-acetyltransferase 2 (NAT2). ScienceDaily Magazine editor@sciencedaily.com Sat, 09 Feb 2008 05:00:00 GMT http://news.yahoo.com/s/nm/20080122/hl_nm/smoking_radiation_dc_1 http://tobacco.org/news/258521.html Cigarette smoking dramatically increases the risk that a woman who has undergone radiation treatment for breast cancer will develop lung cancer later on, a new study shows. Radiation after mastectomy may be considered for some high-risk breast cancer patients, Dr. Elizabeth L. Kaufman and colleagues from Columbia University in New York City point out in their report. However, radiation can cause many complications, including increasing the likelihood that a patient will develop lung cancer 10 or more years after treatment, they add. U.S. Newswire Owner:gschen@yahoo-inc.com (SOURCE: Journal of Clinical Oncology, January 20, 2008.) Tue, 22 Jan 2008 05:00:00 GMT http://www.bordermail.com.au/news/bm/national/1034484.html http://tobacco.org/news/256165.html SMOKING more than doubles the risk of developing breast cancer among women with a strong family history of the disease, a study of Australians has revealed. The major international review is the first to show a connection between the disease and tobacco in women with the highest risk breast cancer genes, BRCA1 or BRCA2. About half of women with faulty versions of these genes will develop cancer by the age of 70. . . . The review, published in the journal Breast Cancer Research and Treatment, analysed data collected from 780 women involved in large breast cancer trials, including more than 300 from the Melbourne-based Australian Breast Cancer Family study. The Border Mail webeditor@bordermail.com.au Australia Tue, 04 Dec 2007 05:00:00 GMT http://www.springerlink.com/content/36740134711h7476/ http://tobacco.org/news/255860.html Conclusions These results indicate that smoking is associated with increased risk of breast cancer before age 50 years in BRCA1 and BRCA2 mutation carriers. If confirmed, they provide a practical way for carriers to reduce their risks. Previous studies in prevalent mutation carriers have not shown smoking to increase risk of breast cancer, but are subject to bias, because smoking decreases survival after breast cancer. Breast Cancer Research and Treatment Boyd@uhnres.utoronto.ca Australia Tue, 27 Nov 2007 05:00:00 GMT http://uninews.unimelb.edu.au/articleid_4819.html http://tobacco.org/news/255850.html Women who carry a faulty BRCA1 or BRCA2 gene - which puts them at high risk of developing breast cancer - will further double their risk if they smoke, says a new international study. University of Melbourne researchers were key collaborators on the study, currently published online in the journal Breast Cancer Research and Treatment. University of Melbourne janinesj@unimelb.edu.au Australia Tue, 27 Nov 2007 05:00:00 GMT