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• Cigarette smoking in middle age and a long-term risk of impaired activities of daily living: NIPPON DATA80  

Introduction: Few studies have reported the relationship between smoking in middle age and long-term risk of impaired activities of daily living (ADL).

Methods: We analyzed 2,276 men and women aged 47–59 years at the baseline survey of NIPPON DATA80 in 1980. At the follow-up survey in 1999, ADL was surveyed among 1890 survivors. Multivariate-adjusted odds ratio (AOR) and 95% CI of impaired ADL or of composite outcome of either death or impaired ADL according to baseline smoking status were calculated by multiple logistic regression analyses. . . .

Discussion: Smoking in middle age would increase future risks of impaired ADL. Smoking cessation may be important to prevent future impairment of ADL as well as death.

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