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Stop-Smoking Aid Chantix Sparks Safety Concerns 

Researchers Focus on 26 Reports of Chantix and Aggression or Violence; Drugmaker Says No Cause-Effect Evidence Exists
Jump to full article: WebMD, 2010-07-27
Author: Kathleen Doheny WebMD Health News

Intro:

Evidence is accumulating that the stop-smoking drug Chantix is linked with unprovoked acts and thoughts of aggression and violence, according to a new report.

The drug is so potentially dangerous that its use should be restricted to exclude police, military, and similar occupations in which workers carry weapons, says Thomas J. Moore, senior scientist for drug safety and policy at the Institute for Safe Medication Practices in Horsham, Pa. Moore is one of three co-authors of the new report on the drug, published in the Annals of Pharmacotherapy.

"My colleagues and I have been concerned about the safety profile of [Chantix] since our first report [warning of adverse events] in 2008," Moore tells WebMD.

But others, including a smoking cessation researcher and a spokesperson for Pfizer, which makes Chantix, disagreed strongly. They point out that the number of adverse events is far outweighed by the benefits of the drug

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