Jump to full article: MedPage Today, 2010-03-19
Author: Charles Bankhead, Staff Writer, MedPage Today
Intro: Action Points
* Explain to patients that this study showed no increased lung cancer risk in women taking estrogen therapy.
* The study was not designed to evaluate lung cancer risk.
* Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered preliminary until published in a peer-reviewed journal.
SAN FRANCISCO -- Unopposed estrogen therapy (ERT) did not increase lung cancer incidence or mortality risk in the Women's Health Initiative (WHI).
Women randomized to ERT and placebo had similar rates of all lung cancer, non-small cell lung cancer, and small cell lung cancer. An identical pattern emerged from a mortality analysis, Rowan Chlebowski, MD, reported here at the Society of Gynecologic Oncologists meeting.
The results contrast with those of a previous WHI analysis showing a significant lung cancer mortality hazard among women treated with combined estrogen-progestin (HRT) therapy.
"It looks like maybe progestin is the bad component,"
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