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Smoking significantly increases risk of aneurysm in people with certain genes  

For people who carry common gene variants, cigarette smoking greatly increases the risk that a blood vessel in the brain will weaken and balloon out -- called an aneurysm -- which could be life-threatening if it ruptures, according to research presented at the American Stroke Association's International Stroke Conference 2010.

Researchers reported on two new studies from the Familial Intracranial Aneurysm (FIA) project, a multinational collaboration funded by the National Institutes of Neurological Disorders and Stroke to study genetic and other risk factors in families with at least two members affected by intracranial aneurysm.

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