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Taiwan study proves relation between tobacco, lung cancer 

A Taiwanese research had further identified the reason why tobacco causes lung cancer and other smoking-related diseases and was made the cover story of the February issue of the world is leading biomedical journal, The Journal of Clinical Investigation.

The study revealed the mechanism of how tobacco-specific carcinogen causes lung tumors. It showed that the key ingredient of tobacco carcinogen, nicotine-derived nitrosamine ketone (NNK), would induce the accumulation of a protein, DNA methyltranferase 1 (DNMT1), which inhibits the tumor suppressor genes, and lead to lung cancer.

It also showed that the accumulation of DNMT1 in lung cancer patients who smoked continuously correlates with poor recovery.

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