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A Rigorous and Comprehensive Validation: Common Genetic Variations and Lung Cancer  

Jump to full article: Cancer Epidemiology, Biomarkers & Prevention, 2010-02-08

Intro:

Conclusions: None of the five candidate SNPs in lung cancer risk can be confirmed in our study. The previously reported association could be explained by disparity in tobacco smoke exposure and chronic obstructive pulmonary disease history between cases and controls. Instead, we found rs4324798 to be an independent predictor in small cell lung cancer survival, warranting further elucidation of the underlying mechanisms.

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