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When the smoke clears: Molecular link between tobacco carcinogen and cancer 

Jump to full article: ScienceDaily, 2010-01-20

Intro:

A team of researchers, led by Yi-Ching Wang, at National Cheng Kung University, Taiwan, Republic of China, has uncovered a potential mechanism by which the tobacco-specific carcinogen NNK promotes lung tumor formation and development.

Specifically, they suggest that NNK induces the accumulation of a protein known as DNMT1 in the nucleus and that this protein silences genes that suppress tumor formation. . . .

The research appears in the Journal of Clinical Investigation.

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