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A Case-Control Study of Smoking and Bladder Cancer Risk: Emergent Patterns Over Time  

* JNCI J Natl Cancer Inst * Volume 101, Number 22 * Pp. 1553-1561
Jump to full article: Journal of the National Cancer Institute, 2009-11-17

Intro:

Conclusions: Smoking-related risks of bladder cancer appear to have increased in New Hampshire since the mid-1990s. Based on our modeling of pack-years and intensity, smoking fewer cigarettes over a long time appears more harmful than smoking more cigarettes over a shorter time, for equal total pack-years of cigarettes smoked. . . .

Contribution

Overall, current smokers, compared with never-smokers, had more than a five fold higher risk of bladder cancer. Among New Hampshire residents, there was a statistically significant progressive increase over each time period in bladder cancer risk among both former and current smokers compared with never-smokers.

Implications

The smoking-related risks of bladder cancer appear to have increased over time, at least among New Hampshire residents.

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