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Patch Plus Lozenge Beats Other Stop Smoking Regimens  

Action Points

* Explain that after controlling for tighter P-values, the patch-plus-lozenge modality was the one of five treatments with significantly higher smoke-free abstinence rates after six months compared with placebo.

Out of five different smoking cessation modalities, the nicotine patch plus lozenges proved to be the most efficacious, researchers said.

After controlling for tighter P-values, the combination was the only modality with significantly higher smoke-free abstinence rates after six months compared with placebo, Megan E. Piper, PhD, of the University of Wisconsin School of Medicine and Public Health, Madison, and colleagues reported in the November issue of Archives of General Psychiatry.

The findings suggest that a "combination pharmacotherapy comprising the nicotine patch and an ad libitum nicotine replacement therapy should be routinely considered for use as a smoking cessation treatment," the researchers said.

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