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· Health/Science
· COPD
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Jump to full article: MedPage Today, 2009-10-06
Author: Nancy Walsh, Contributing Writer, MedPage Today
Intro: Action Points
* Explain to interested patients that no additional benefits were seen when inhaled corticosteroids were added to beta-agonist therapy in chronic obstructive pulmonary disease.
* Also tell them that the combination therapy was associated with increased risk of pneumonia and other adverse events.
Inhaled corticosteroids did not improve the efficacy of long-acting beta agonist therapy among patients with chronic obstructive pulmonary disease (COPD), a systematic review has found.
The combination treatment failed to significantly decrease the number of severe COPD exacerbations (RR 0.91, 95% CI 0.82 to 1.01) or all-cause mortality (RR 0.90, 95% CI 0.76 to 1.06), according to Gustavo J. Rodrigo, MD, of the Hospital Central de las Fuerzas Armadas in Montevideo, Uruguay, and colleagues.
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