Jump to full article: New Kerala.com (in), 2008-04-15
Intro: Although nicotine is known to affect neutrophils, there has been no study until now of the mechanisms at work when nicotine is present during neutrophil differentiation.
David Scott from the Oral Health and Systemic Disease Research Group at the University of Louisville School of Dentistry, Kentucky, USA, along with a team of international colleagues decided to investigate how nicotine influenced the differentiation process.
The authors suggest the processes they observed as contributing to impaired neutrophil function partially explain chronic tobacco users' increased susceptibility to bacterial infection and inflammatory diseases. . . .
The study is published in the open access journal BMC Cell Biology.
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