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A strategy of harm reduction is likely to succeed, the committee said, only if manufacturers have the incentive to develop and market products that reduce harm; consumers are accurately informed of all known and potential consequences of using these products; if advertising and labeling are firmly regulated to prevent false or misleading claims; if basic, clinical, and population studies are conducted to indicate reduced harm; and if health effects of using these products are continually monitored. Most important, the committee stressed the need to make harm reduction a component of a comprehensive national approach that includes the prevention of smoking initiation and relapse, as well as the promotion of smoking cessation.<I>Clearing the Smoke: Assessing the Science Base for Tobacco Harm Reduction</I>