Daily Doc: PM, Mar 26, 1980: PM on Nicotine and heart disease


Daily Doc: PM on Nicotine and heart disease


Title: Progress Report of the Epidemiology Division of the American Health Foundation
PM, Mar 26, 1980
Bates #: 1000129639/9640

September 5, 2000

In this Philip Morris (PM) internal memo, PM scientist Ray Fagan indicates that nicotine may lower the heart's threshold to ventricular fibrillation, an inefficient pumping mode wherein the heart "flutters" and fails to pump blood efficiently. Fagan further observes that this condition can result in sudden death:
"This type of arrythmia is frequently the cause of sudden death in cardiovascular disease."
CITATION
Title: Progress Report of the Epidemiology Division of the American Health Foundation
Type of Document: Memo
Author: R. Fagan
Recipient: Dr. T.S. Osdene
Date: 19800326
Site: Tobacco Documents Online (TDO): http://my.tobaccodocuments.org/tdo/view.cfm?CitID=1811824 Or on the Philip Morris (PM) Document Site: http://www.pmdocs
Bates No. 1000129639/9640
Length: 2 pages
URL: http://www.pmdocs.com/cgi-bin/rsasearch.exe?bool=Did:1000129639/9640&if=avpidx
Litigation Usage: None yet
QUOTES
As stated in a number of places in the [American Health Foundation] Report, nicotine is the 'highly suspect agent in the onset of myocardial infarction.' I doubt whether this is true. If nicotine is involved in cardiovascular disease it may be responsible for the lowered threshold to ventricular fibrillation. This type of arythmia is frequently the cause of sudden death in cardiovascular disease.


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Anne Landman, Regional Program Coordinator
American Lung Association of Colorado, West Region Office
Grand Junction, CO
(970) 245-2120
afoxland@gj.net
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